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DIGITAL CONTENT CENTER: HYPOPHOSPHATASIA (HPP)
| HPP Publications | HPP Infographics | HPP Patient Videos | ESPE-ESE 2025 HPP Symposium
Hypophosphatasia (HPP) is a rare, inherited, metabolic, systemic disease caused by deficient activity of the alkaline phosphatase (ALP) enzyme. HPP affects people of all ages with a broad spectrum of skeletal and nonskeletal clinical manifestations, high disease burden, and substantial negative impact on quality of life.
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1. Bangura A et al. Cureus 2020;12(6):e8594.

Read or download PDFs of important peer-reviewed HPP publications.

<<Read or download 2 infographics on functional assessments in children and adults with HPP.>>
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Watch videos of children and adults with HPP sharing their stories for deeper patient insights.​
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Download our symposium invitation and watch video messages from our faculty, Professors Agnès Linglart, Florian Barvencik, and Kathryn M. Dahir.
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